Pharmacogenetic of antirheumatic treatments: clinical implications

new clinical implications of opiate maintenance treatments

Clinical implications of pharmacogenetic variation on the effects of statins.

The last decade has seen an increase in the trend of HMG-CoA reductase inhibitor (statin) usage in the Western world, which does not come as a surprise noting that the latest American Heart Association heart and stroke statistics indicate an alarming prevalence of 80  million Americans (one in three) with one or more forms of diagnosed cardiovascular disease (CVD). Meta-analysis of several larg...

Pharmacogenetic tests for antipsychotic medications: clinical implications and considerations

Optimizing antipsychotic pharmacotherapy is often challenging due to significant variability in effectiveness and tolerability. Genetic factors influencing pharmacokinetics and pharmacodynamics may contribute to some of this variability. Research studies have characterized these pharmacogenetic relationships, and some genetic markers are now available as clinical tests. These advances in pharma...

New Clinical Implications of Opiate Maintenance Treatments

Opiate addiction is a chronic mental illness with severe repercussion in personal and public health. Various medicaments have been subjected to research in order to find a proper treatment, methadone is the most and wide used drug, buprenorphine/naloxone is the most recent ones, but other choices have been proposed such as prescribing heroin (1). The mentioned treatments, are considered as main...

Modern Treatment Approaches in Psychoses. Pharmacogenetic, Neuroimagistic and Clinical Implications

We approached the theme of modern pharmacological treatment strategies and the implication of pharmacogenetic testing in the management of child and adolescent psychoses. Our research was conducted in the period 2010 2015 on 210 patients, as follows: 150 children and adolescents with psychosis – a group of 75 children-G1, who benefited in choosing the pharmacotherapy from pharmacogenetic testin...